In honor of his birthday, San Francisco banker Nicholas Van Orton, a financial genius and a cold-hearted loner, receives an unusual present from his younger brother, Conrad: a gift certificate to play a unique kind of game. In nary a nanosecond, Nicholas finds himself consumed by a dangerous set of ever-changing rules, unable to distinguish where the charade ends and reality begins.
In a future society in the era of indefinite eugenics, humans are set on a life course depending on their DNA. Young Vincent Freeman is born with a condition that would prevent him from space travel, yet is determined to infiltrate the GATTACA space program.